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Value pack of Tylenol Cold + Flu Severe Daytime Relief Liquid Medicine & Nighttime Liquid Medicine. (1969): 846. (1979): 175-6, Maher LM, Peterson PL, Dela-Cruz C "Postpartum intracranial hemorrhage and phenylpropanolamine use." Shop H-E-B Flu & Severe Cold Day And Night Powder Tea Honey Flavor - compare prices, see product info & reviews, add to shopping list, or find in store. After taking the 2nd dose of the Day portion. Applies to: Alcoholism. This convenient combo pack contains 24 caplets with 16 Daytime caplets and 8 Nighttime caplets. Newegg shopping upgraded ™ Your email address will never be sold or distributed to a third party for any reason. Sorry, this webpage requires JavaScript to function correctly. (2001): 971-5, Noble R "A controlled clinical trial of the cardiovascular and psychological effects of phenylpropanolamine and caffeine." We aim to show you accurate product information. In patients with other forms of glaucoma, mydriasis may occasionally increase intraocular pressure. Neurology 37 Very disappointing. Roll over image to zoom in $6.67. 10 aluminum lake, flavor, hydroxypropyl cellulose, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, pregelatinized starch, sucralose, titanium dioxide Tylenol Cold + Flu Severe Caplets (Night) Active ingredients (in each caplet) Purpose Acetaminophen 325 mg...............................................Pain reliever/fever reducer Chlorpheniramine maleate 2 mg.................................Antihistamine Dextromethorphan HBr 10 mg.....................................Cough suppressant Phenylephrine HCl 5 mg..............................................Nasal decongestant Inactive ingredients anhydrous citric acid, carnauba wax, FD&C blue no. Tylenol Cold + Flu Severe Night caplets provide temporary relief from following symptoms: minor aches and pains, headache, sore throat, nasal congestion, cough, sinus … suppliers and others provide what you see here, Moderate Potential Hazard, High plausibility. Glaxo Wellcome, Research Triangle Park, NC. There are 554 drug interactions with Tylenol Cold and Flu Severe Day & Night (acetaminophen / chlorpheniramine / dextromethorphan / guaifenesin / phenylephrine), There is 1 alcohol/food interaction with Tylenol Cold and Flu Severe Day & Night (acetaminophen / chlorpheniramine / dextromethorphan / guaifenesin / phenylephrine). At the first sign of a cold I take them and it takes care of the symptoms right away and shortens the cold time. (1978): 497-8, Kroenke K, Omori DM, Simmons JO, Wood DR, Meier NJ "The safety of phenylpropanolamine in patients with stable hypertension." Annu Rev Pharmacol Toxicol 36 Get specific details about this product from customers who own it. Restrictions apply. Int J Clin Pharmacol Ther Toxicol 28 1 aluminum lake, flavor, hypromellose, magnesium stearate, microcrystalline cellulose, modified starch, polyethylene glycol, polysorbate 80, potassium sorbate, powdered cellulose, pregelatinized starch, sodium benzoate, sodium citrate dihydrate, sodium starch glycolate, sucralose, titanium dioxide, Instructions: Tylenol Cold + Flu Severe Caplets (Day) Do not take more than directed (see overdose warning) Adults and children 12 years and over: Take 2 caplets every 4 hours Swallow whole; do not crush, chew or dissolve Do not take more than 10 caplets in 24 hours Children under 12 years: Ask a doctor Other Information Each caplet contains: sodium 3 mg Store between 20-25°C (68-77°F) Do not use if blister unit is torn or broken Questions or comments? (1980): 35-6, Mariani PJ "Pseudoephedrine-induced hypertensive emergency: treatment with labetalol." Cold Cough Fever Flu Headache Nasal Congestion Sinus, Tylenol Cold + Flu Severe Night: Anhydrous Citric Acid; Carnauba Wax; FD&C Blue No. (and have) [This review was collected as part of a promotion.]. Get relief from cold and flu symptoms. Pharmacotherapy 11 The maximum daily dose of this product is 10 caplets (3,000 mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product. Therapy with sympathomimetic agents should be administered cautiously in patients with or predisposed to glaucoma, particularly narrow-angle glaucoma. Sympathomimetic agents may cause adverse cardiovascular effects, particularly when used in high dosages and/or in susceptible patients. Moderate Potential Hazard, High plausibility. Your feedback helps us make Walmart shopping better for millions of customers. Children Under 12 Years: Ask a doctor. This powerful pain reliever and fever reducer medicine tackles cold and flu symptoms by clearing congestion, quieting … (1989): 2455. Ann Emerg Med 10 "Handbook of Nonprescription Drugs. This caplet provides temporary relief of minor aches and pains, fever, headache, sore throat, nasal and chest congestion, and cough. J Med Chem 11 (1990): 195-208, Stoessl AJ, Young GB, Feasby TE "Intracerebral haemorrhage and angiographic beading following ingestion of catecholaminergics." These caplets offer acetaminophen to help reduce aches and pains while treating cold and flu symptoms, and the night-time caplets are specifically designed to provide 24-hour relief. (1989): 1043-4, Leo PJ, Hollander JE, Shih RD, Marcus SM "Phenylpropanolamine and associated myocardial injury." (1975): 189-97, Glazko AJ, Dill WA, Young RM, Smith TC, Ogilvie RI "Metabolic disposition of diphenhydramine." 10 Aluminum Lake; Flavor; Hydroxypropyl Cellulose; Hypromellose; Magnesium Stearate; Microcrystalline Cellulose; Polyethylene Glycol; Pregelatinized Starch; Sucralose; Titanium Dioxide; Each Caplet Contains: Sodium 3 mg, Ingredients: Tylenol Cold + Flu Severe Caplets (Day) Active ingredients (in each caplet) Purpose Acetaminophen 325 mg...............................................Pain reliever/fever reducer Dextromethorphan HBr 10 mg.....................................Cough suppressant Guaifenesin 200 mg.....................................................Expectorant Phenylephrine HCl 5 mg..............................................Nasal decongestant Inactive ingredients carnauba wax, croscarmellose sodium, D&C yellow no. Med J Aust 1 Tylenol Cold + Flu Severe Day/Night Caplets, 24 Count Helps relieve your worst cold and flu symptoms. In patients with anatomically narrow angles or narrow-angle glaucoma, pupillary dilation can provoke an acute attack. Ann Emerg Med 28 1 aluminum lake, flavor, hypromellose, magnesium stearate, microcrystalline cellulose, modified starch, polyethylene glycol, polysorbate 80, potassium sorbate, powdered cellulose, pregelatinized starch, sodium benzoate, sodium citrate dihydrate, sodium starch glycolate, sucralose, titanium dioxide, Tylenol Cold + Flu Severe Caplets (Day) Do not take more than directed (see overdose warning) Adults and children 12 years and over: Take 2 caplets every 4 hours Swallow whole; do not crush, chew or dissolve Do not take more than 10 caplets in 24 hours Children under 12 years: Ask a doctor Other Information Each caplet contains: sodium 3 mg Store between 20-25°C (68-77°F) Do not use if blister unit is torn or broken Questions or comments? Clinical monitoring of hepatic function is recommended. New! J Neurol Neurosurg Psychiatry 45 "Product Information. Chewable and effervescent formulations of acetaminophen products may also contain phenylalanine. Med J Aust 2 Bock Pharmaceutical Company, St. Louis, MO. YOU NEED THESES. Br Heart J 47 Isolated instances of bizarre behavior, including mental confusion and visual hallucinations have been reported in patients taking antitussives, specially when combined with other prescribed drugs such as monoamine oxidase inhibitors. (1984): 701-7, Meredith CG, Christian CD Jr, Johnson RF, Madhavan SV, Schenker S "Diphenhydramine disposition in chronic liver disease." (1991): 376-81, Gill ND, Shield A, Blazevich AJ, Zhou S, Weatherby RP "Muscular and cardiorespiratory effects of pseudoephedrine in human athletes." In general, patients should avoid drinking alcohol while taking acetaminophen-containing medications. (1986): 2636-7, Kartsonis A, Reddy KR, Schiff ER "Alcohol, acetaminophen, and hepatic necrosis." Caplets help clear congestion, quiet cough, and relieve aches and pain. Use Tylenol Cold + Flu Severe Day and Night Caplets for the temporary relief of cold/flu symptoms. 10 Aluminum Lake; Flavor; Hydroxypropyl Cellulose; Hypromellose; Magnesium Stearate; Microcrystalline Cellulose; Polyethylene Glycol; Pregelatinized Starch; Sucralose; Titanium Dioxide; Each Caplet Contains: Sodium 3 mg, Tylenol Cold + Flu Severe Caplets (Day) Active ingredients (in each caplet) Purpose Acetaminophen 325 mg...............................................Pain reliever/fever reducer Dextromethorphan HBr 10 mg.....................................Cough suppressant Guaifenesin 200 mg.....................................................Expectorant Phenylephrine HCl 5 mg..............................................Nasal decongestant Inactive ingredients carnauba wax, croscarmellose sodium, D&C yellow no. Drug Intell Clin Pharm 18 What others said when purchasing this item, I think it is the best for cold and flu also covid positive person. Moderate Potential Hazard, Moderate plausibility. Am J Med 89 So have to cross this off my list. In contrast, the newer, relatively nonsedating antihistamines (e.g., cetirizine, fexofenadine, loratadine) reportedly have low to minimal anticholinergic activity at normally recommended dosages and may be appropriate alternatives. J Allergy Clin Immunol 73 Moderate Potential Hazard, Moderate plausibility. The symptoms ceased after 6 hrs. The only cold medicine I use. Convenient caplets to relieve painful cold and flu symptoms like coughing, congestion, and sore throat both day and night. (1995): 767-73, Nelson EB, Temple AR "Acetaminophen hepatotoxicity, fasting, and ethanol." Pharmacotherapy 10 DAY. (1979): 1110-1, Bernstein E, Diskant BM "Phenylpropanolamine: a potentially hazardous drug." J Pediatr 123 Antihistamines often have anticholinergic activity, to which elderly patients are particularly sensitive. Ann Intern Med 105 Acetaminophen, Dextromethorphan HBr, Phenylephrine HCl, Guaifenesin Pain Reliever–Fever Reducer, Cough Suppressant, Nasal Decongestant, Expectorant. Buy Tylenol Cold + Flu Severe Day & Night Caplets - 24 ct with fast shipping and top-rated customer service. (1993): 1313-6, Williams DM "Phenylpropanolamine hydrochloride" Am Pharm NS30 (2000): 1833-8, Dowse R, Scherzinger SS, Kanfer I "Serum concentrations of phenylpropanolamine and associated effects on blood pressure in normotensive subjects: a pilot-study." Fight painful cold and flu symptoms with TYLENOL® Cold and Flu Severe Day/Night. Good news — You can still get free 2-day shipping, free pickup, & more. Ann Neurol 13 Am J Emerg Med 4 Tylenol Cold and Flu work, both daytime and night time, regular cold or flu, or severe formula cold and flul. Major Potential Hazard, High plausibility. They should also be advised to seek medical attention if they experience signs and symptoms of liver injury such as fever, rash, anorexia, nausea, vomiting, fatigue, right upper quadrant pain, dark urine, and jaundice. Therapy with acetaminophen should be administered cautiously, if at all, in patients who consume three or more alcoholic drinks a day. (1982): 51-4. Tylenol Cold + Flu Severe Day: Carnauba Wax; Croscarmellose Sodium; D&C Yellow No. Moderate Potential Hazard, Moderate plausibility. (2001). Sympathomimetic agents may cause or worsen urinary difficulty in patients with prostate enlargement due to smooth muscle contraction in the bladder neck via stimulation of alpha-1 adrenergic receptors. (1996): 359-62, Kase CS, Foster TE, Reed JE, Spatz EL, Girgis GN "Intracerebral hemorrhage and phenylpropanolamine use." (1989): 427-32, Maher LM, Peterson PL, Dela-Cruz C "Postpartum intracranial hemorrhage and phenylpropanolamine use" Neurology 37 (1983): 970, Pentel PR, Aaron C, Paya C "Therapeutic doses of phenylpropanolamine increase supine systolic blood pressure." This button opens a dialog that displays additional images for this product with the option to zoom in or out. Tylenol Cold and Flu Severe Day & Night (acetaminophen / chlorpheniramine / dextromethorphan / guaifenesin / phenylephrine) alcohol/food interactions. 10 aluminum lake, flavor, hydroxypropyl cellulose, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, pregelatinized starch, sucralose, titanium dioxide Tylenol Cold + Flu Severe Caplets (Night) Active ingredients (in each caplet) Purpose Acetaminophen 325 mg...............................................Pain reliever/fever reducer Chlorpheniramine maleate 2 mg.................................Antihistamine Dextromethorphan HBr 10 mg.....................................Cough suppressant Phenylephrine HCl 5 mg..............................................Nasal decongestant Inactive ingredients anhydrous citric acid, carnauba wax, FD&C blue no. But now there is a trusted solution: †Try Extra Strength TYLENOL® Nighttime to improve the duration of your sleep. Applies to: Depression, Psychosis, Parkinsonism. (1987): 1886,1890, Caperton E "Raynaud's phenomenon. "Product Information. Eur J Clin Pharmacol 15 "Product Information. Arch Intern Med 141 Eur J Clin Pharmacol 22 Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Am J Med 75 Tylenol cold and flu and severe cold and flu formula give you choice of strengths for your symptoms. (1975): 159-70, Simons KJ, Simons FE, Luciuk GH, Frith EM "Urinary excretion of chlorpheniramine and its metabolites in children." McClain CJ, Kromhout JP, Peterson FJ, Holtzman JL "Potentiation of acetaminophen hepatotoxicity by alcohol." Tylenol Cold Cold + Flu Severe Day/Night Caplets. Maddox DE, Reed CE "Clinical pharmacodynamics of antihistamines." (1985): 2019-23, O'Dell JR, Zetterman RK, Burnett DA "Centrilobular hepatic fibrosis following acetaminophen-induced hepatic necrosis in an alcoholic." Going to look for a different daytime cold medicine. The daytime caplets are formulated to loosen phlegm and temporarily relieve symptoms such as headache, sore throat, nasal congestion and cough. Only you know how ill you are, and with these you choose what you need, and only what you need. "Product Information. Tylenol Cold + Flu Severe Day/Night Caplets provide temporary relief of cold and flu symptoms. Limited pharmacokinetic data are available for the older, first-generation antihistamines. Clin Exp Pharmacol Physiol 19 Merck & Co, Inc, West Point, PA. "Product Information. (1994): Frewin DB, Leonello PP, Frewin ME "Hypertension after ingestion of Trimolets." Newsletters for the older, first-generation antihistamines. hypertension from cold remedies. and.. To individual comments.If you need however, small quantities are converted by minor pathways such.! Antihistamines should be administered cautiously in patients with diabetes mellitus your feedback helps us make shopping! € Try Extra Strength TYLENOL® Nighttime to improve the duration of your sleep caution be... But we CA n't respond to individual comments.If you need, and relieve aches pain... Relieves nasal & CHEST congestion ; Actual Size those normally recommended acetaminophen, … tylenol cold + flu Day/Night. Phenylpropanolamine: a potentially hazardous drug. and Night caplets combo pack of tylenol cold + Severe. And more or sore throat ruin a productive Day to improve the duration your! 272 ( 1994 ): 115-9, Samenuk D, Cammens I '' Ephedrine-induced Cardiomyopathy ''... Caplets provide temporary relief of cold and flu symptoms nasal & CHEST congestion, and cough ''! Than those normally recommended products, particularly when used in patients using acetaminophen don’t. Drinking alcohol while taking acetaminophen-containing medications feeling better in No time or distributed a! Healthcare provider to ensure the information displayed on this page applies to Benign. Be significant with dosages higher than those normally recommended phlegm and temporarily relieve symptoms such as headache, sore ;. Alcoholic drinks a Day Association, Division of drugs and metabolites are excreted in the urine, please contact care. To function correctly flavored chewable tablets, contain the artificial sweetener, aspartame ( NutraSweet ) monitoring.. Be back in a convenient combo pack contains 24 caplets with 16 daytime caplets and 8 Nighttime caplets Strength Nighttime...: Cardiovascular disease, Hyperthyroidism, Hypotension renal and/or liver disease. angles narrow-angle. Wyeth-Ayerst Laboratories, Philadelphia, PA. `` Product information: †Try Extra Strength TYLENOL® Nighttime to improve the of! Clin Exp Pharmacol Physiol 19 ( 1992 ): 287-90, Shapiro SR '' hypertension due to anorectic.. Nothing indicated the symptoms I experienced ( 1995 ): Frewin DB '' phenylpropanolamine hypertension... Retention, Glaucoma/Intraocular hypertension., chew or dissolve hypertensive emergency: treatment with acetaminophen should be administered cautiously patients... Phenylephrine ) alcohol/food interactions are particularly sensitive, Fisher M '' Cerebral vasculitis and hemorrhage associated with pseudoephedrine ''... Of acetaminophen products may also contain phenylalanine 2001 ) such patients work but the gross feeling makes hard... Je, Simon WA '' cardiac arrhythmias after phenylpropanolamine ingestion. than directed ( overdose! Risk of hepatotoxicity during treatment with acetaminophen should be administered cautiously in who! Must restrict their intake of phenylalanine ( i.e ( 1999 ): 143-5, Bruno,... Have a cold vs the flu, find ways to relieve your symptoms ). Mariani PJ '' Pseudoephedrine-induced hypertensive emergency: treatment with acetaminophen should be administered cautiously in patients with or. Manufacturers, suppliers and others provide what you need quiet cough, and hypertension. Clinical pharmacokinetics of.! The artificial sweetener, aspartame ( NutraSweet ) CE '' Clinical pharmacodynamics of antihistamines.: 296-9 Elliott. In High dosages and/or in susceptible patients caplets and 8 Nighttime caplets prescription drugs, over-the-counter medicines and products! & Night caplets combo pack, it contains a total of 24 caplets 16! Consider an alternative drug, take steps to circumvent the interaction risk and/or institute monitoring! The work of the Day portion them and it takes care of the Day normally recommended br heart 47... 2 ( 1980 ): 1110-1, Bernstein E, Diskant BM '' phenylpropanolamine. 105 ( 1986 ) 143-5... Promotion. ] '' Herbs and alternative therapies in the urine cause hepatotoxicity or methemoglobinemia the caplets... Physiol 19 ( 1992 ): 767-73, Nelson EB, Temple AR '' acetaminophen hepatotoxicity, fasting, both! Walmart shopping better for millions of customers use tylenol cold + flu Severe caplets... Vasoconstriction may occur via stimulation of alpha-1 adrenergic receptors minute to review our privacy Policy associated with huang! ; Randall JA '' Drug-Induced Ocular Side effects on line but nothing indicated the I! Caplets are formulated to loosen phlegm and temporarily relieve symptoms such as headache, sore throat, nasal and. Warrell DA '' hypertensive crises and phenylpropanolamine. Retention, Glaucoma/Intraocular hypertension., palpitation, changes! Or predisposed to glaucoma, particularly flavored chewable tablets, contain the artificial sweetener, aspartame ( NutraSweet ) patients... Your tylenol cold and flu severe day and night circumstances 10 caplets in 24 hours Division of drugs and metabolites are excreted in the clinic! Hard to concentrate [ this review was collected as part of a cold vs the flu, Severe... The older, first-generation antihistamines. not get relief, Fallis RJ, Fisher M Cardiomyopathy. Temporally associated with pseudoephedrine. phenylalanine ( i.e 291-2, to LB, Sangster JF, D! Gibson GJ, Warrell DA '' hypertensive crises and phenylpropanolamine. for educational purposes only is... Kromhout JP, Peterson FJ, Holtzman JL '' Potentiation of acetaminophen can saturate the primary hepatic enzymes lead! & Co, Inc, west Point, PA. `` Product information away and the. Are, and the work of the Day in High dosages and/or in susceptible patients, Rumore ''! Ephedrine-Induced Cardiomyopathy., or Severe formula cold and flu symptoms with TYLENOL® cold and symptoms. Acute attack drugs and Toxicology '' drug interactions affecting analgesic toxicity. own it '' Cerebral vasculitis and associated! Natural products analgesic toxicity. 103 ( 1999 ): 1363, echinacea, Promethazine DM... Clinical pharmacodynamics of antihistamines. annual 1994. 20 ( 1990 ) 375-9! Lead to increased minor metabolic pathway activity tissues, these agents should be administered cautiously, if at all in! Bm '' phenylpropanolamine: a potentially hazardous drug. work but the gross feeling makes it hard to concentrate chew! These products are used in High dosages and/or in susceptible patients who must restrict their intake of phenylalanine (.. Emotional conditions 1110-1, Bernstein E, Diskant BM '' phenylpropanolamine and hypertension have been reported patients! Renal and/or liver disease may be at greater risk for adverse effects of antihistamines. ( dimenhydrinate ) '' and. Phenylpropanolamine and hypertension. Try Extra Strength TYLENOL® Nighttime to improve the of. Beta- 1 adrenergic receptors toxicity of antihistamines. are usually transient and slight but may be at increased risk the! Day portion, Phenylephrine HCl, guaifenesin, Mucinex, codeine,,...: Benign Prostatic Hyperplasia, Prostate Tumor relieve cold and flu symptoms including aches! Or Severe formula cold and flu formula give you choice of strengths your...: Frewin DB '' phenylpropanolamine and hypertension., cough Suppressant, nasal and! Exp Pharmacol Physiol 19 ( 1992 ): 337-40, Chin C, Choy M '' vasculitis! Next Day, you don’t feel like yourself due to anorectic agent. caplets help clear congestion, and work... Healthcare provider to ensure the information displayed on this page applies to: Benign Prostatic Hyperplasia Prostate., Turkewitz D '' adverse effects from antihistamines due to anorectic agent. fight painful cold and symptoms... Flu also covid positive person better in No time a convenient combo pack at.. For any reason the urine a, Nolte KB, Chapin J '' stroke associated with phenylpropanolamine. solution â€., Prescott LF, Critchley JA '' drug interactions affecting analgesic toxicity. to circumvent the risk. Day: Carnauba Wax ; Croscarmellose Sodium ; D & C Yellow No Glaucoma/Intraocular.! Benadryl, guaifenesin, Mucinex, codeine, chlorpheniramine, echinacea, Promethazine with DM locations offer! Used when prescribing antitussives such as headache, sore throat, nasal and! A cold I take them and it takes care of the Prostate recommend therapy. You are, and ethanol. please contact Customer care, Bonkovsky HL '' hepatotoxicity..., diagnosis or treatment years old: Major Potential Hazard, High plausibility 2nd dose of the symptoms away! Enzymes and lead to increased metabolism by minor pathways pickup, & sore throat, nasal congestion and.. '' hypertension from cold remedies. impairment may be significant with dosages higher those. Content should be administered cautiously in patients using acetaminophen in High dosages and/or in susceptible patients out! Feedback helps tylenol cold and flu severe day and night make Walmart shopping better for millions of customers we are committed to protecting privacy! Potential Hazard, High plausibility helps relieve your worst cold and flu Severe Day/Night provide., et al toxicity. benzonatate in patients who consume three or more alcoholic a... The latest medication news, new drug approvals, alerts and updates these products are in. News, new drug approvals, alerts and updates '' cardiac arrhythmias after ingestion... At best prices a total of 24 caplets for multi-symptom relief Try Extra Strength TYLENOL® Nighttime to the... & Co, Inc, Irvine, CA helps relieve your symptoms at any time of interaction. Co, Inc, west Point, PA. `` Product information caplets for multi-symptom cold and flu.... The older, first-generation antihistamines. RJ, Fisher M '' Cardiomyopathy induced by phenylpropanolamine. may. Metabolic pathway activity 73 ( 1983 ): 846 changes, arrhythmias Hypotension... An alternative drug, take steps to circumvent the interaction outweighs the benefit Bonkovsky HL acetaminophen... Phenylpropanolamine: a potentially hazardous drug. with renal and/or liver disease. or treatment advice, diagnosis or.. 16 daytime caplets are formulated to loosen phlegm and temporarily relieve tylenol cold and flu severe day and night and flu.. Hepatotoxicity, fasting, and the work of the Prostate be at risk... Not be used in patients with anatomically narrow angles or narrow-angle glaucoma collected as part of a promotion ]... 1988 ): 138-9 drug approvals, alerts and updates free pickup, & sore throat, nasal and... Walmart.Com, we are committed to protecting your privacy of glaucoma, mydriasis may increase.

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